Common tests to check for syphilis antibodies include: ![]() If you have these antibodies, it means you have a syphilis infection now, or you had a syphilis infection that was treated in the past. Usually, the second test looks for antibodies that your immune system makes only to fight off syphilis. If the result of your screening test shows you have antibodies linked to syphilis infections, you'll need a second test to confirm whether or not you have syphilis. Venereal Disease Research Laboratory (VDRL) test, which can be done on blood or spinal fluid.Rapid plasma reagin (RPR), which is a blood test.Screening tests for syphilis usually include: But other things may trigger your immune system to make these antibodies, such as autoimmune diseases, other infections, and vaccinations. In most cases, the first step is a screening test to check for antibodies that are linked to having a syphilis infection. Syphilis testing usually involves two steps. Antibodies are proteins that your immune system makes when it finds harmful substances in your body. Syphilis tests screen for and diagnose syphilis by looking for certain antibodies in your blood. Other names: rapid plasma reagin (RPR), Venereal Disease Research Laboratory (VDRL), fluorescent treponemal antibody absorption (FTA-ABS) test, agglutination assay (TP-PA), darkfield microscopy Finding and treating the infection early can also prevent the spread of syphilis to others. Syphilis tests can help diagnose the infection in the early stages, when it's easiest to cure. In rare cases, untreated syphilis can even cause death. Treatment can still help, but it will not reverse the damage. If it's not treated and develops to a late stage, it can cause permanent damage to your health. Syphilis is easiest to cure in the early stages of infection. You could pass the infection to someone else. So, you could have syphilis and not know it. In the beginning, the signs and symptoms may be mild. Each stage has different signs and symptoms that can last for weeks, months, or even years. It can also pass from a pregnant person to their baby. It is a bacterial infection that spreads through vaginal, oral, or anal sexual contact with someone who has the infection. ![]() Syphilis is one of the most common sexually transmitted diseases (STDs). Syphilis tests are used to screen for and diagnose syphilis.
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